Yes, a change in facial proportions is a natural effect of weight loss during Mounjaro therapy. As body fat is lost, the face may become slimmer and its contours more defined. The changes most commonly affect the cheeks, jawline and temples. For many people, this leads to a more harmonious appearance, although others may feel that their face has lost some of its „fullness”. The final result depends on the rate of weight loss, age and individual anatomy.